by staff | Aug 8, 2017 | Death, Fentanyl, Heroin, Naloxone, Narcan, Opioids
If you believe you or someone else is experiencing fentanyl overdose symptoms, please call 911 right away. Fentanyl is an extremely potent potentially fatal drug and should not be underestimated.
Fentanyl, also known as fentanil, is an incredibly potent synthetic opioid pain medication with a rapid onset and short duration of action. This drug is considered to be around 50 to 100 times more potent than morphine, while some fentanyl analogues such as carfentali, which are designed to mimic the pharmacological effects of the original drug, may be as much as 10,000 times more potent than morphine. Fentanyl brand names include:
- Actiq
- Duragesic
- Fentora
- Sublimaze
Individuals who abuse opioids, particularly heroin, are more likely to ingest fentanyl, knowingly or unintentionally. This puts them at an even higher risk of overdose.
In 2015 alone, 33,091 people died due to overdose on opioids like fentanyl.
Learning how to recognize the indications of a fentanyl overdose and getting professional substance abuse treatment may save a life.
Fentanyl Overdose Symptoms: Side Effects of Fentanyl
As an extremely potent opioid drug, fentanyl is very carefully prescribed and dosed by medical professionals. Those who abuse fentanyl may use the drug outside of prescription guidelines or without a prescription altogether, which can drastically increase their risk of lethal overdose.
Fentanyl’s most common side effects of Fentanyl use include
- Asthenia(weakness)
- Diarrhea
- Nausea
- Constipation
- Dry mouth
- Somnolence
- Confusion
- Sweating
Some of the less common side effects of Fentanyl use include:
- Abdominal pain
- Anxiety
- Depression
- Anorexia and weight loss
- Headache
- Fatigue
- Dizziness
- Nervousness
- Hallucinations
- Flu-like symptoms
- Dyspepsia(indigestion)
- Dyspnea (shortness of breath)
- Hypoventilation
- Urinary retention abuse
Fentanyl Overdose Symptoms: Risks of abuse
With a powerful drug like fentanyl the risk of abuse is exceedingly high, especially considering the drug’s medical use is so limited to treating extreme cases. So when people take fentanyl in higher doses or more frequently than prescribed it of course elevates their risk for serious side effects and experiencing fentanyl overdose symptoms.
As far as recreational use, fentanyl is extremely dangerous. Using this drug in any way other than intended, such as snorting or injecting it, is not only illicit abuse of the chemical, but potentially life-threatening. In recent years drug dealers have been mixing fentanyl powder with heroin to increase potency or compensate for low-quality heroin. This illegally manufactured, non-pharmaceutical fentanyl cut into other substances caused an outbreak of overdose deaths in the United States and Canada over the past several years.
Combining fentanyl with other drugs can have effects that either compound the already severe side effects of fentanyl or contradict the effect and cause more chaos in the body. Using fentanyl with other substances is very hazardous, especially with drugs such as:
- Alcohol
- Stimulants
- Benzodiazepines
- Antidepressant medication
The Center for Disease Control and Prevention (CDC) conducted a study recently that showed:
- 82% of fentanyl overdose deaths involved illegally manufactured fentanyl
- Only 4% were suspected to originate from a prescription
National Forensic Laboratory Information System reported:
- 942 fentanyl seizures in 2013
- 3,344 fentanyl seizures in 2014
Fentanyl Overdose Symptoms: Signs to Look For
Being able to address a possible overdose means being able to recognize and understand some of the possible fentanyl overdose symptoms. While one of these may not be a definite indication, noticing a combination of symptoms may be a more serious issue.
A person experiencing fentanyl overdose symptoms may present with the following overdose signs:
- Pinpoint pupils
- Pale skin
- Nausea
- Choking sounds or gurgling/snoring noises
- Weak muscles
- Dizziness
- Confusion
- Extreme sleepiness
- Very low blood pressure
- Dangerously slowed or stopped breathing
- Blue skin tinge nails and lips
- Loss of consciousness
- Intensely slowed heart beat
- Coma
- Seizure
- Death
The effects of fentanyl overdose symptoms on an individual’s respiratory system and heart rate are the most serious relating to risk of death or permanent damage. Not only can this lead to coma or death, but even after surviving the overdose there can still be complications.
If not treated immediately, the impact of fentanyl overdose symptoms on the heart and respiratory system may cause residual problems such as permanent brain damage.
Fentanyl Overdose Symptoms: How Much Is Too Much?
It is difficult to determine the exact dose it would take for someone to experience fentanyl overdose symptoms. According to some medical professionals, 250 micograms of fentanyl might represent a lethal dose of fentanyl. However, most individual’s using heroin and other drugs are unaware that they have ingested the drug at all, let alone know how much fentanyl is in the doses.
At the end of the day, fentanyl overdose symptoms can vary depending on the individual, and the amount it takes to overdose will vary to. Some elements that impact the odds of overdosing includes:
- Other drugs taken
- Height
- Weight
- Age
- Physical condition
In the event of an overdose of fentanyl you should seek immediate emergency medical assistance. Some cases require several doses of Narcan (Naloxone), the opioid overdose antidote, to stabilize the individual suffering from an overdose. Even if you have access to Narcan or Naloxone yourself, always contact emergency medical services to get assistance, because when the antidote wears off the overdose could return, or there may be other severe complications.
Opiate medications and street drugs have done a great deal of damage these past few years. Synthetic opioids like fentanyl have raised the risks and increased the death rates in a big way. Far too many lives are ruined, or brought to an abrupt end, because of overdoses when there is real help out there. Don’t wait until after an overdose. If you or someone you love is struggling with substance abuse or addiction, please call toll-free now.
CALL NOW 1-888-922-5398
by Justin Mckibben | Aug 7, 2017 | Heroin, Methadone, Naloxone, Narcan, Opioids, Prescription Drugs
Narcan is a brand name for the opioid overdose antidote Naloxone hydrochloride. Technically speaking, the opioid antagonist is a synthetic congener of Oxymorphone that is structurally different in that the methyl group on the nitrogen atom is replaced by an allyl group. In the past couple years Narcan has gradually become a household name. With the opioid epidemic in America continuing to ravage many communities across the nation, Narcan has become one of the first lines of defense. For some people, while they know now what this powerful substance is, they are still unsure how to use Narcan to stop an opioid overdose.
NOTE: All instructions in this article come from the Harm Reduction Coalition website. You can also look for Narcan/Naloxone training in your area. Different brands may provide more specific instructions. Be sure to real labels and warnings on Narcan or Naloxone kits.
How to Use Narcan: More about Narcan
Narcan works by blocking the effects of opioids and can actually reverse an overdose in order to get medical attention to someone who is in need. The life-saving opiate antidote is used for the complete or partial reversal of opioid depression, including respiratory depression. An opioid overdose can cause breathing to slow down or stop completely, putting someone’s life in immediate danger. Some examples of opioid overdoses Narcan may be used to reverse include the drugs:
- Heroin
- Morphine
- Codeine
- Oxycodone
- Methadone
- Vicodin
One major plus is that Narcan has no euphoric effects and cannot get someone “high” so abuse is not an issue. The overdose antidote is essentially harmless if there are no opiods present in someone’s system. If given to a person who has not taken opioids, there will be no effect. Narcan can still be effective when alcohol or other drugs are present with opiates. However, some of the incredibly potent synthetic drugs such as Fentanyl and carfentanil have shown to be somewhat resistant to Narcan treatment, meaning those overdosing due to carfentanil require extra doses to be stabilized.
Administration to opioid-dependent individuals may cause symptoms of opioid withdrawal, including:
- Restlessness
- Agitation
- Nausea
- Vomiting
- Fast heart rate
- Sweating
There are other measures that can be taken to help ease these symptoms as well.
How to Use Narcan: Intravenous Infusion
The most rapid onset of action is achieved by intravenous administration, which is recommended in emergency situations. Narcan may be diluted for intravenous infusion in either:
- Normal saline
- 5% dextrose solutions
2 mg of Narcan mixed in 500 mL of either solution provides a concentration of 0.004 mg/mL. Narcan should not be mixed with preparations containing:
- Bisulfite
- Metabisulfite
- Long-chain or high molecular weight anions
- Any solution having an alkaline pH
No drug or chemical agent should be added to the mixture unless its effect on the chemical and physical stability of the solution has first been established. To use the injectable Narcan:
- If the person is not breathing perform rescue breathing for a few quick breaths.
- Use a long needle (called an IM or intramuscular needle) which about 1 – 1 ½ inch. NOTE: If there isn’t a big needle, a smaller needle is OK and inject under the skin, but big needles are better.
- Remove the pop off orange top from the vial
- Draw up 1cc (1cc=1mL=100u) of antidote into the syringe
- Inject into a muscle, the best being thighs, upper, outer quadrant of the butt, or shoulder. NOTE: Inject straight in to make sure to hit the muscle.
- After injection, continue rescue breathing 2-3 minutes.
- If there is no change in 2-3 minutes, administer another dose and continue to breathe for them.
NOTE: If the second dose of naloxone does not revive them, something else may be wrong— either it has been too long and the heart has already stopped, there are no opioids in their system, or the opioids are unusually strong and require more naloxone (such as Fentanyl or carfentanil).
For more information, you should be able to find instructions in the Narcan kit, or inquire when picking up a Narcan kit about any opportunities to receive more in-depth training.
How to Use Narcan: Nasal Spray
Another resource that has helped make huge progress in fighting opioid overdose death rates is the Narcan (or Naloxone) nasal spray kit. The variation has made training people to administer the overdose antidote much easier and much less dangerous. Without needles, the nasal spray system helps eliminate the issue of blood contamination.
According to instructions posted through the Harm Reduction Coalition, there are about 5 steps for how to use Narcan with nasal spray.
- If the individual is not breathing perform rescue breathing for a few quick breaths.
- Attach the nasal atomizer (applicator) to the needleless syringe and assemble the glass cartridge of naloxone.
- Tilt the head back and spray half of the naloxone up one side of the nose (1cc) and half up the other side of the nose (1cc).
- If there is no breathing or breathing continues to be shallow, continue to perform rescue breathing for them while waiting for the naloxone to take effect.
- If after about 3 to 5 minutes there is no change, administer another dose of naloxone and continue to breathe for them.
NOTE: If the second dose of naloxone does not revive them, something else is wrong—either it has been too long and the heart has already stopped, there are no opioids in their system, or the opioids are unusually strong and require more naloxone (such as Fentanyl or carfentanil).
Regardless of if you use an intravenous Narcan kit or a nasal spray kit, Narcan should never be used as substitute for emergency medical care. In the event of an opioid overdose one should always call 911 right away, even if the individual wakes up. Narcan can wear off between 30-90 minutes, while the effects of the opioids can last much longer. It is possible that after Narcan wears off the overdose can return.
Also look into Narcan training programs in your area.
How to Use Narcan: Get More Help
When someone has to be revived from an opioid overdose it can be a pretty clear cut indication that something needs to be done in order to help them stay safe.
Another difficult aspect of how to use Narcan is that naloxone can cause uncomfortable opioid withdrawals. Because Narcan blocks the action of opioids in the brain, people can wake up feeling withdrawals practically immediately and try to use again. Of course this could result in another overdose.
Beyond administering Narcan to save someone’s life, take this as an opportunity to seek resources and start a conversation about getting them the help they need. Preserving life is important, but saving a life by changing a life can make a world of difference. There are empowering and innovative addiction treatment programs that specialize in addressing this chronic, progressive and fatal substance use disorder. After surviving an overdose presenting someone with the opportunity to get treatment may be the best chance they get.
Holistic addiction treatment allows people who were once hopeless build the foundation of hope again. If you or someone you love is struggling with substance abuse or addiction, please call Palm Healthcare Company. We want to help.
CALL NOW 1-888-922-5398
by Justin Mckibben | Aug 1, 2017 | Depression, Dual Diagnosis, Heroin, Mental Health, Mood Disorders, Suicide
(This content is being used for illustrative purposes only; any person depicted in the content is a model)
For many who have struggled with substance abuse it comes as no surprise that a link can be drawn between their drug or alcohol use and their mental health. A lot of people who struggle with addiction have experienced some form of emotional distress, trauma or abuse that has made a definite impact on their lives. While this may not be the sole reason behind their use, issues concerning mental health can contribute to drug or alcohol use in a dramatic way. With heroin and depression, the two tend to feed off of one another, creating an intense and deeper connection.
Understanding Depression
Depression is a very common but also very serious mood disorder, also referred to as:
- Major depressive disorder
- Clinical depression
This mental health condition causes a variety of symptoms that impact how an individual thinks, feels, and handles their day to day lives. A depression diagnosis depends on symptoms being present for at least two weeks, and some forms of depression will differ, or develop under unique circumstances. Some specific forms of depression include:
-
Persistent Depressive Disorder (Dysthymia)
This is a depressed mood lasting for at least two years. Sometimes the episodes of major depression is experienced in periods of less severe symptoms, but still the symptoms persist for two years or more.
-
Psychotic Depression
This is pretty straight forward. It happens when someone experiences severe depression along with some form of psychosis, such as:
These psychotic symptoms typically revolve around a particular depressive subject like guilt, poverty or illness.
-
Seasonal Affective Depression
This is the onset of depressive symptoms during winter months when there is less natural sunlight, which is why some call it ‘winter depression’. It is commonly characterized by:
- Social withdrawal
- Increase in sleep
- Weight gain
This depression typically disappears during spring and summer months as better weather returns, but comes back around every year.
-
Perinatal Depression
Many women experience relatively mild depressive and anxiety symptoms after delivery, usually only lasting around two weeks. However, perinatal depression is much more serious.
Mothers with perinatal depression experience full-blown major depression during pregnancy or after delivery, commonly known as postpartum depression. Feelings that accompany perinatal depression include:
These can make it difficult for new mothers to complete daily care activities for themselves and/or for their babies.
-
Bipolar Disorder
While bipolar disorder is technically different from depression, individuals with bipolar disorder do experience episodes of intensely low moods that qualify as major depression- referred to as ‘bipolar depression’.
However, someone with bipolar disorder also experiences extreme high moods, either irritable or euphoric in nature. These moods are also called ‘mania’, or the less intense with are called ‘hypomania’. This is why bipolar disorder was once called ‘manic depressive disorder’.
Beyond these five there are other forms of depression, and symptoms of depression may vary from person to person. But for most people with depression the symptoms they do experience are consistent on an almost daily basis.
Psychology of Heroin
For those who don’t know, heroin is a synthetic drug produced from morphine. Morphine is a powerful analgesic derived from the opium poppy plant. The effects of heroin are a result of the substance binding with receptors in the brain that respond to opiates. Once ingested, heroin converts to morphine in the brain, and this potent compound effects the brain in ways that influence psychology.
Morphine slows the neurological activity in the brain, creating sedation. This sedation creates the desired effect of many heroin users, which is the sense of profound relaxation.
Yet, the National Alliance on Mental Illness warns that people with psychiatric disorders (such as depression) are more likely to experience very negative side-effects. So while people with depression may try to use heroin to numb themselves to feelings of sadness, guilt or despair, they actually create a chemical reaction in the brain that exacerbates their depressive symptoms.
Heroin and Depression
Heroin and depression have a symbiotic relationship that creates a viscous cycle. The two fuel each other. An individual may use heroin to try and escape their depressive feelings, but using heroin frequently worsens symptoms such as:
Thus these feelings make the depression worse, the individual will use more heroin to escape, and the cycle continues.
With heroin and depression, the physical consequences of heroin use can also cause severe emotional distress. Physical effects of heroin that can increase feelings of depression include:
- Respiratory illness
- Blood-borne disease
- Muscular weakness
- Vascular damage
And heroin’s impact on an individual’s personal life can make depression even worse, such as:
- Financial problems
- Job loss
- Legal trouble
- Relationship issues
Again, these issues can cause a heroin user to abuse the drug more in order to cope with these difficulties, which continues to feed into their problems and exacerbate the issues even more.
Withdrawal from Heroin and Depression
Withdrawal from heroin is one of the typical reasons that many people trying to quit the drug are unsuccessful. These unpleasant side effects of not having the drug often pushes people trying to give up heroin back to the drug just to feel relief, and for those with depression the withdrawals from heroin can seem even more relentless.
Trying to abruptly discontinue heroin use without the help of medical detox will cause uncomfortable and sometimes extremely painful symptoms such as:
- Nervousness
- Intense cravings
- Restlessness
- Involuntary leg movement
- Sweating
- Muscle pain
- Sleeping problems
- Runny nose
- Stomach Pain
- Nausea
- Vomiting
- Diarrhea
Heavy use over an extended period can also lead to seizures. But while the physical withdrawal symptoms are already pretty bad, the psychological side effects can seem impossible to overcome, especially for someone with depression or other mental health issues.
Dual Diagnosis Treatment for Heroin and Depression
One of the most critical parts of treatment for heroin users with depression is to find the root cause of the depression, which is also one of the most challenging aspect of recovery for heroin users. Depression is not just a bad mood, and it does not simply stem from one source. Some of the most common sources of depression include:
- Genetics
- Brain chemistry
- Psychological trauma
- Physical disability
- Stressful social environment
- Drug or alcohol abuse
Dual diagnosis treatment is crucial for someone struggling with heroin and depression because the two conditions have such similar symptoms, which make each other worse. In many cases, it is difficult to even discover what came first, depression or heroin addiction. Either way, a huge factor to overcoming heroin and depression is with comprehensive and holistic dual diagnosis treatment.
Simultaneously addressing both issues and giving equal attention to both conditions gives way for more complete recovery. If one of the two is ignored, then it has the potential to eventually cause a relapse into the other. The deeper connection with heroin and depression is that these each of them is commonly inspired by similar circumstances, including genetics and trauma. Both will thrive through the impact of the other. Both are damaging and potentially fatal. But there is also help for each, and when treated in tandem they can each be overcome.
At Palm Healthcare Company, the idea of treating all parts of each individual is the core concept of our holistic approach to substance use disorder treatment. We believe that by providing personalized and effective care for each individual helps create lasting health, freedom and happiness in every aspect of life. If you or someone you love is struggling, please call toll-free now.
CALL NOW 1-888-922-5398
by Justin Mckibben | May 5, 2017 | Addiction, Detox, Drug Abuse, Heroin, Opioids, Withdrawal
Heroin (diacetylmorphine) is a Schedule I controlled-substance in the United States and is considered by many to be the most addictive drug in the world when compared to other more popular illicit drugs. Heroin is typically associated with the highest likelihood of developing an addiction both psychologically and physically.
Given the fact that the country is facing the most deadly drug epidemic in American history thanks to the opioid overdose outbreak, heroin abuse is now a primary concern facing most of the nation. Other opioids, like prescription painkillers, have contributed to the rising rates of heroin use, and the addition of other potent drugs like fentanyl, heroin is more dangerous than ever.
Heroin overdose is currently one of the top causes of accidental death. People use more than the body can handle and it shuts down. Also, the withdrawals of heroin can be particularly difficult. So how long does heroin stay in your system?
How Long Does Heroin Stay in Your System: Important Elements
When asking how long does heroin stay in your system we have to examine some of the important elements that impact the effects of heroin on the body. Heroin is typically injected intravenously to make a faster impact, but it is also smoked or snorted. Heroin has longer lasting effects compared to drugs like cocaine and meth, but it also has a shorter half-life of only approximately 30 minutes.
What does half-life of heroin mean? Essentially, when an individual uses a single dose of heroin, it will take about 30 minutes for half of the drug in the person’s system to be flushed out. However, some studies actually suggest that this half-life is as short as 3-8 minutes, not 30.
The accurate amount of time it would take is not cut and dry. The half-life of heroin depends on a number of factors for each individual, including:
- Height
- Weight
- Age
- Genetics
- Body fat
- The amount taken
- Purity of the drug
- Method of use
- Metabolism
- Health of the liver
- Kidney health
- Hydration
Not all bodies are the same, so of course not all bodies will be able to get rid of heroin at the same exact rate. A body with more fatty tissue and less hydration will probably retain the chemicals longer than someone well-hydrated with a lean build.
How Long Does Heroin Stay in Your System: Drug Testing for Heroin
Some might hope they can measure the presence of heroin in the system based on drug tests. Of course the length of time a drug is detectable with a drug test depends directly on the rate at which heroin leaves the body. Different drug tests often have different lengths of time they measure, so one might be able to tell you someone used heroin, but it may not be particularly active in the body.
Approved drug tests through the Food and Drug Administration (FDA) for heroin use:
- Blood
- Saliva
- Urine
- Hair follicle
Heroin is typically no longer detectable in a person’s urine after just 2 days, but some tests have detected positive results in up to 7 days.
Blood and saliva tests aren’t often used for most opioids because they have such a short half-life. It can only take about 5-6 hours for heroin to be undetectable for these tests, but in some cases it may actually last up to 2 days.
The only effective long-term test for traces of heroin is the hair follicle test, which can detect heroin for up to 3 months or more. However, if you are trying to find out if heroin is still active in the body, the long-term doesn’t really help.
Many tests now look for heroin metabolites, which are what is created when the liver metabolizes the drug. These stay in the system much longer than the actual intoxicant, so while you can detect the presence of the metabolites, the drug itself isn’t necessarily active. However, many believe that among long-term and/or frequent heroin users, the drug may actually remain in a person’s system for much longer than detectable on a drug test.
How Long Does Heroin Stay in Your System: Withdrawal
One reason many people will want to know how long heroin stays in the system is for the sake of overcoming their withdrawal symptoms. Especially for those who are familiar with suffering through these painful periods of abstinence, the question of how long does heroin stay in your system is about avoiding extended discomfort.
Withdrawal symptoms of heroin include:
- Sweating
- Insomnia
- Malaise
- Extreme anxiety
- Depression
- Itchiness
- Excessive yawning and sneezing
- Runny nose
- Cold sweats
- Chills
- Severe muscle and bone aches
- Nausea
- Vomiting
- Diarrhea
- Fever
- Cramp-like pains
- Involuntary spasms in the legs, arms, and neck
Heroin withdrawals will not be the same for everyone. The same things that impact how long it stays in the system will also impact how severe the withdrawals are. Other substances that are used along with heroin will also have an impact on how serious the withdrawals can be and how long they may persist.
It has been estimated that heroin withdrawal symptom can start within 6-12 hours from the last dose and may be present up to 5-10 days.
How Long Does Heroin Stay in Your System: Overdose Danger
One big reason things like the half-life matter is because of how it increases the risks of overdose.
If we say that after ingesting heroin approximately 50% of the drug has been cleared from the body in somewhere between 8-30 minutes, what tends to happen during this time is that many people assume by time their “high” ends, most of the heroin is already fully cleared from their system. However, when the “high” ends, up to 50% of the heroin will still be in your system, and so will its metabolites! So while some people think the high wears off that quick so they may think it’s safe to do more, there is still a fair amount of that drug present in the body.
Although heroin is quickly metabolized and eliminated from the body, its metabolites remain present for a longer duration. When heroin is used it is de-acetylated into 6-monoacetylmorphine (6-MAM). This chemical then metabolizes into morphine. Morphine’s half-life is estimated to be between 1.5 and 7 hours. As a result, the morphine in the body created by using heroin could stay in your system for 1.60 days before it is entirely eliminated.
So when we ask how long does heroin stay in your system, it isn’t a one-size-fits-all thing. What we can say is that one thing the probably contributes a lot to the skyrocketing rates of overdoses and deaths is that people don’t understand the heroin half-life or how long it stays in the system.
The longer the drug is in the system, the harder it will be to detox from it. That is why medical detox is so crucial to effectively and safely getting off of heroin. It also shows why treatment can be critical to lasting recovery. If you or someone you love is struggling, please call toll-free now.
CALL NOW 1-888-922-5398
