by Justin Mckibben | Aug 14, 2017 | Death, Drug Abuse, Fentanyl, Heroin, Naloxone, Narcan, Opioids, Prescription Drugs
As we have seen time and time again, the opioid epidemic all across America has not been confined to one substance. It takes the shape of prescription painkillers, illicit heroin and even the more potent synthetic opioids like fentanyl. With the gradual progression of this poisonous outbreak, we have seen the stakes get higher and higher. Prescription opioids contributed to a growing population of heroin users. Dealers lacing heroin with synthetics like fentanyl led to higher overdose rates. Then the highly dangerous, frequently lethal carfentanil was added to the mix and now just being around the drugs can almost kill you.
With the addition of fentanyl and carfentanil to the illicit drug world comes a very real and potentially lethal new threat- secondary exposure overdose.
What is Secondary Exposure?
Secondary exposure is also referred to as secondary contamination or second-hand exposure. It is a term usually used with things like asbestos poisoning or mesothelioma. Sometimes it is even used to describe the effects of radiation. It is when people come into contact with gasses or substances that can be absorbed into the body and do very real damage.
The most common comparison you could make is to second-hand smoke, which is when people smoking cigarettes expose others to the toxic gas they and the cigarette release into the air. Second-hand smoke can cause very real health problems, including some cancers. The most terrible aspect of it being that the individual who gets sick doesn’t even have to smoke themselves.
With drug use secondary exposure overdose has now become a real risk thanks to synthetic opioids. Law enforcement and other officials tell us that some of these dangerous substances must be handled with the utmost caution. The news coming out of Ohio this week is just another example of how hazardous these drugs have become.
Ohio Nurses Experience Secondary Exposure Overdose
At Affinity Medical Center, a hospital in Massilion, Ohio, three nurses helped treat an overdose patient. After cleaning the room where the individual was treated, the three nurses were overcome by secondary exposure. They got sick and shortly after lost consciousness.
Detective Shaun Dadisman states,
“They were cleaning up the room and started to feel sick. And then that left them waking up in a hospital bed,”
According to the investigators in this case, the three nurses were treated with Narcan. The opioid overdose antidote Narcan is the brand name for Naloxone, which is used to reverse the effects of opioids on the respiratory system. The local law enforcement believe the substance the nurses were exposed to was fentanyl. Thankfully, all three nurses are said to have recovered.
A union representing nurses at the hospital intends to meet with hospital officials to review protocols for environmental contamination. A spokeswoman from the hospital states that the institution does have effective policies, which isn’t out of the question.
Police Officer Needs Narcan after Secondary Exposure Overdose
Just this summer, a police officer in a very similar situation almost died from an accidental overdose due to secondary exposure. Officer Chris Green was responding to a drug call when the incident occurred. The drug he came in contact with at the time was so powerful that even though officer Green said he was wearing gloves and a mask as he searched a suspect’s car, he still ended up being severely impacted by the substance. Merely by ending up with a white substance on his shirt officer Green needed to be revived with not just one, but multiple doses of Narcan.
How Does Secondary Exposure Overdose Happen?
Detective Shaun Dadisman spoke more about the dangers of opioid overdose through secondary exposure. Dadisman states,
“It shuts down your breathing. It shuts down your system so you get to the point where you’re not breathing on your own. And you need that boost and that Narcan is what takes that away so it helps you to recover quickly,”
Fentanyl and other opioids like carfentanil present a whole new level of danger concerning secondary exposure. The drugs are so intoxicating that law enforcement and medical personnel are now forced to come up with new policies and protocols just to handle an individual who may be overdosing on these drugs to protect themselves and others. Dadisman stated,
“I was actually stuck by a needle from an individual on a heroin overdose, so I had to run through all of the testing myself,”
The opioid epidemic now doesn’t just present an elevate risk of death to those who are using these drugs. Opioid abuse now poses a very real and deadly danger to those who work to save the lives of users every day. The greatest danger some of these drugs prevent is that of the unknown. As Dadisman points out,
“I think there will be continued changes – gloves, masks. And the problem with our first responders, police officers and our nurses and stuff, is you don’t know immediately what you’re dealing with. After the fact, you may know, but it may be too late.”
So now every day these synthetic opioid drugs don’t just threaten the lives of people who consume them, whether knowingly or not, but also the people closest to them.
So what can be said about secondary exposure overdose? Well, it is safe to say that with some of the most powerful drugs that are out there simply getting some on your skin or breathing it in, even on accident, can cause life-threatening illness. While hopefully this concept does not start a panic, it is a reality that more people should probably be aware of. Whether people are leaving the drug around others, consuming the drug in public places or being revived by loved ones and first responders, the fact is the drugs are stronger and more life-threatening than ever. The fact that a dose of Narcan might not save someone on the first shot should be enough to push for more awareness and more focus on finding a way to fight back.
So, what more can be done about the possibility of secondary exposure overdose?
If you or someone you love is struggling with opioids do not hesitate to get help. The rates for overdoses and opioid-related deaths are far too high to keep gambling with your life. Protect your loved ones and your future. If you or someone you love is struggling, please call toll-free now. We want to help.
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by Justin Mckibben | Aug 9, 2017 | Drug Policy, Law Enforcement, Naloxone, Prescription Drugs, Recovery, Stigma
President Donald Trump promised a “major briefing” via his favorite publication… twitter… this Tuesday morning. Many people were expecting something big related to the request from the national opioid commission to declare a state of emergency for the opioid epidemic. But alas, this was not the case. President Trump made no announcement on new policies in the fight against opioids. Instead, he made a comment that sounds a lot like Nancy Reagan telling everyone to ‘just say no’ in the 80s, and we all know how well that worked.
This is concerning to so many who put stock in President Trump when he said he would make fighting the opioid epidemic a priority. Yet, so many feel like he is absent on the subject when it comes to establishing any initiatives or taking proactive action.
President Trump vowed on Tuesday that the United States will “win” the battle against the heroin and opioid outbreak. But instead of presenting a plan to support and reinforce treatment initiatives and other programs, the focus on his comments were claims to-
“- protect innocent citizens from drug dealers that poison our communities.”
The closer we look at the administration’s latest actions, the more it seems like this administration prefers the failed ‘just say no’ and War on Drugs mentality than actually offering a progressive answer.
President Trump Says Drugs are Bad
Probably the one part people are most annoyed with is when President Trump stated:
“Maybe by talking to youth and telling them ‘no good, really bad for you in every way’, but if they don’t start it will never be a problem.”
I feel like most of us did a good old fashion face-palm on this one… because DUH! We know drugs are bad (thanks Mr. Mackey) and we know talking to kids about drugs matters. That is why programs like Drug Abuse Resistance Education (D.A.R.E.) have been around for decades. However, we also know from D.A.R.E.’s track record that this kind of program hasn’t been particularly successful at stopping drug use either!
While giving this latest briefing from his 17 day “working vacation” from his golf club in Bedminster, New Jersey, President Trump also stated:
“The best way to prevent drug addiction and overdose is to prevent people from abusing drugs in the first place,”
“I’m confident that by working with our health care and law enforcement experts, we will fight this deadly epidemic and the United States will win.”
Now while it is true that addiction can’t technically develop if someone never uses substances, this still sounds a lot like ‘just say no’, which we all know does not work as a drug policy. Prevention is key and maybe with more detail about Trump’s plan on how to prevent drug use we could see where this comment is going. But as it stands, these comments just sound like more of the same.
After all, Trump’s Attorney General Jeff Session does seem to agree with the old War on Drugs tactics. Why, we may never know.
It is incredibly frustrating to advocates and experts involved in the addiction recovery community, as well as for citizens all across the nation who are hoping for some real change. Why- because we know that ‘just say know’ failed. We tried to just tell kids that drugs are bad for them and not to do them, but the epidemic still happened! And needless to say, just saying no is not going to help us with the overwhelming rates of addiction, overdose and death that we are already dealing with.
Far beyond that, understanding and overcoming addiction is about a lot more than just knowing its bad for you.
Is President Trump Ignoring Suggestions?
The president himself appointed the opioid commission, chaired by Republican New Jersey Governor Chris Christie. Only a week ago the panel urged President Trump to “declare a national emergency”, citing the tragically high overdose and death rates across the country. In the report issued by the opioid commission there were numerous recommendations that many were hopeful would come to fruition as soon as possible. Among these recommendations there is:
- Expanding treatment facilities across the country
- Educating and equipping doctors about the proper way to prescribe pain medication
- Equipping all police officers with the anti-overdose remedy Naloxone
All of these suggestions seem like they would make a pretty big impact on the current predicament. Empowering treatment providers in more of the U.S. can help get more addicts off the streets and introduce them to the option of getting well. Putting more power in the hands of doctors to safely and effectively provide medications could help reduce the staggeringly high prescription drug abuse rates. Giving the overdose antidote to more first responders could save so many more lives.
And yet, President Trump did not address a single one of these recommendations, or event suggest that one of them was on his current to-do list.
Instead, he went back to his go-to argument for solving all of our problems… our borders. Again, President Trump doesn’t give any indication as to planning for expanding treatment or Naloxone access. Nope… he just promises to be-
“-very, very strong on our Southern border.”
Did he talk about training doctors in order to avoid issues with prescription drugs? Nope. Instead he claimed:
“We’re talking to China, where certain forms of man-made drug comes in and it is bad,”
Yes, again we understand… ‘drugs are bad… mmmkay.’ But seriously, this is not the first time that this administration has shifted the focus from helping treat those who have suffered from drug addiction to ‘tough on crime’ tactics and border security. But time and time again experts in law enforcement and drug policy insist that the answer is not in attacking the supply side, but in treating those who suffer now.
Health and Human Services Secretary Tom Price told reporters they haven’t taken anything off the table, but that they believe at this point the necessary resources and focus can be addressed without an official declaration. However, looking at what declaring the emergency would have done, why would doing it be a bad thing?
Why a National Emergency Matters
The reality is, we are all well aware of the severity of the opioid epidemic by now. However, declaring a national emergency does actually count for something.
If President Trump were to declare a national emergency it would speak volumes to the scope of the issue on a national platform. Also, coming from one of the highest authorities in the nation, it would have opened the door to making those other suggestions happen.
According to Juliet Sorensen, a professor at Northwestern University Pritzker School of Law, Trump’s declaration could have:
- Allowed the executive branch to direct federal funds to expand treatment facilities
- President Trump would have also been able to direct funds to equip police with Naloxone
- Allowed him to provide the FBI, the Drug Enforcement Agency and other law enforcement agencies with more money to focus on the manufacturers and smugglers of dangerous drugs like fentanyl
But maybe one of the biggest impacts it could have had would have been on the rest of the House and the Senate. Fighting the opioid epidemic is one of the very few topics in politics right now that has bipartisan congressional support. Declaring a national emergency could give President Trump the perfect opportunity to unite both sides of the aisle and create cooperation and momentum.
This is a vital issue that should absolutely be a priority. Therefore, the idea of returning to an archaic, outdated philosophy concerning drug use is annoying at the least and potentially terrifying for some. The epidemic shows no sign of stopping anytime soon. Maybe it is time to do more than just tell people drugs are bad. If we want to do some good, we need to support each other with compassion.
Palm Healthcare Company values compassionate, comprehensive and innovative holistic treatment opportunities to help save the lives of those that are suffering, and we encourage professionals, community leaders and family members to get involved in helping change lives for the better. If you or someone you love is struggling with substance abuse or addiction, please call toll-free now.
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by Justin Mckibben | Aug 7, 2017 | Heroin, Methadone, Naloxone, Narcan, Opioids, Prescription Drugs
Narcan is a brand name for the opioid overdose antidote Naloxone hydrochloride. Technically speaking, the opioid antagonist is a synthetic congener of Oxymorphone that is structurally different in that the methyl group on the nitrogen atom is replaced by an allyl group. In the past couple years Narcan has gradually become a household name. With the opioid epidemic in America continuing to ravage many communities across the nation, Narcan has become one of the first lines of defense. For some people, while they know now what this powerful substance is, they are still unsure how to use Narcan to stop an opioid overdose.
NOTE: All instructions in this article come from the Harm Reduction Coalition website. You can also look for Narcan/Naloxone training in your area. Different brands may provide more specific instructions. Be sure to real labels and warnings on Narcan or Naloxone kits.
How to Use Narcan: More about Narcan
Narcan works by blocking the effects of opioids and can actually reverse an overdose in order to get medical attention to someone who is in need. The life-saving opiate antidote is used for the complete or partial reversal of opioid depression, including respiratory depression. An opioid overdose can cause breathing to slow down or stop completely, putting someone’s life in immediate danger. Some examples of opioid overdoses Narcan may be used to reverse include the drugs:
- Heroin
- Morphine
- Codeine
- Oxycodone
- Methadone
- Vicodin
One major plus is that Narcan has no euphoric effects and cannot get someone “high” so abuse is not an issue. The overdose antidote is essentially harmless if there are no opiods present in someone’s system. If given to a person who has not taken opioids, there will be no effect. Narcan can still be effective when alcohol or other drugs are present with opiates. However, some of the incredibly potent synthetic drugs such as Fentanyl and carfentanil have shown to be somewhat resistant to Narcan treatment, meaning those overdosing due to carfentanil require extra doses to be stabilized.
Administration to opioid-dependent individuals may cause symptoms of opioid withdrawal, including:
- Restlessness
- Agitation
- Nausea
- Vomiting
- Fast heart rate
- Sweating
There are other measures that can be taken to help ease these symptoms as well.
How to Use Narcan: Intravenous Infusion
The most rapid onset of action is achieved by intravenous administration, which is recommended in emergency situations. Narcan may be diluted for intravenous infusion in either:
- Normal saline
- 5% dextrose solutions
2 mg of Narcan mixed in 500 mL of either solution provides a concentration of 0.004 mg/mL. Narcan should not be mixed with preparations containing:
- Bisulfite
- Metabisulfite
- Long-chain or high molecular weight anions
- Any solution having an alkaline pH
No drug or chemical agent should be added to the mixture unless its effect on the chemical and physical stability of the solution has first been established. To use the injectable Narcan:
- If the person is not breathing perform rescue breathing for a few quick breaths.
- Use a long needle (called an IM or intramuscular needle) which about 1 – 1 ½ inch. NOTE: If there isn’t a big needle, a smaller needle is OK and inject under the skin, but big needles are better.
- Remove the pop off orange top from the vial
- Draw up 1cc (1cc=1mL=100u) of antidote into the syringe
- Inject into a muscle, the best being thighs, upper, outer quadrant of the butt, or shoulder. NOTE: Inject straight in to make sure to hit the muscle.
- After injection, continue rescue breathing 2-3 minutes.
- If there is no change in 2-3 minutes, administer another dose and continue to breathe for them.
NOTE: If the second dose of naloxone does not revive them, something else may be wrong— either it has been too long and the heart has already stopped, there are no opioids in their system, or the opioids are unusually strong and require more naloxone (such as Fentanyl or carfentanil).
For more information, you should be able to find instructions in the Narcan kit, or inquire when picking up a Narcan kit about any opportunities to receive more in-depth training.
How to Use Narcan: Nasal Spray
Another resource that has helped make huge progress in fighting opioid overdose death rates is the Narcan (or Naloxone) nasal spray kit. The variation has made training people to administer the overdose antidote much easier and much less dangerous. Without needles, the nasal spray system helps eliminate the issue of blood contamination.
According to instructions posted through the Harm Reduction Coalition, there are about 5 steps for how to use Narcan with nasal spray.
- If the individual is not breathing perform rescue breathing for a few quick breaths.
- Attach the nasal atomizer (applicator) to the needleless syringe and assemble the glass cartridge of naloxone.
- Tilt the head back and spray half of the naloxone up one side of the nose (1cc) and half up the other side of the nose (1cc).
- If there is no breathing or breathing continues to be shallow, continue to perform rescue breathing for them while waiting for the naloxone to take effect.
- If after about 3 to 5 minutes there is no change, administer another dose of naloxone and continue to breathe for them.
NOTE: If the second dose of naloxone does not revive them, something else is wrong—either it has been too long and the heart has already stopped, there are no opioids in their system, or the opioids are unusually strong and require more naloxone (such as Fentanyl or carfentanil).
Regardless of if you use an intravenous Narcan kit or a nasal spray kit, Narcan should never be used as substitute for emergency medical care. In the event of an opioid overdose one should always call 911 right away, even if the individual wakes up. Narcan can wear off between 30-90 minutes, while the effects of the opioids can last much longer. It is possible that after Narcan wears off the overdose can return.
Also look into Narcan training programs in your area.
How to Use Narcan: Get More Help
When someone has to be revived from an opioid overdose it can be a pretty clear cut indication that something needs to be done in order to help them stay safe.
Another difficult aspect of how to use Narcan is that naloxone can cause uncomfortable opioid withdrawals. Because Narcan blocks the action of opioids in the brain, people can wake up feeling withdrawals practically immediately and try to use again. Of course this could result in another overdose.
Beyond administering Narcan to save someone’s life, take this as an opportunity to seek resources and start a conversation about getting them the help they need. Preserving life is important, but saving a life by changing a life can make a world of difference. There are empowering and innovative addiction treatment programs that specialize in addressing this chronic, progressive and fatal substance use disorder. After surviving an overdose presenting someone with the opportunity to get treatment may be the best chance they get.
Holistic addiction treatment allows people who were once hopeless build the foundation of hope again. If you or someone you love is struggling with substance abuse or addiction, please call Palm Healthcare Company. We want to help.
CALL NOW 1-888-922-5398
by Justin Mckibben | Aug 2, 2017 | Addiction, Drug Abuse, Heroin, Opana, Opioids, Prescription Drugs
America knows all too well the devastation of opioid addiction. With an overdose outbreak that has been progressively damaging and related death rates becoming increasingly alarming, we have reached new depths of drug-induced desperation. Therefore, the news from the Commission on Combating Drug Addiction and the Opioid Crisis is not all that shocking. The panel charged with examining the nation’s opioid epidemic is now urging the President to declare a national public health emergency to combat the ongoing crisis.
When we look at the history of American presidents announcing a ‘state of emergency’ it typically has to do with national security, foreign policy and war, or natural disasters and viral illness. So, to put the issue of addiction up next to these drastic calls to action might just bring a new level of intensity to battling opioid addiction in America.
American overdose deaths involving opioids have quadrupled since 1999. From 2000 to 2015, more than 500,000 people died of drug overdoses. The majority of these overdose deaths have opioids involved.
In America, drug overdoses now kill more people than gun homicides and car crashes combined.
Opioid Commission Calls for Action
The Republican New Jersey Governor Chris Christie was enlisted as the chair of the opioid commission back in March. The opioid commission also includes:
- Democrat Governor Roy Cooper of North Carolina
- Former Democratic Representative Patrick Kennedy of Rhode Island
- Republican Governor Charlie Baker of Massachusetts
At the time the commission was created Chris Christie said the idea behind the administration’s new approach to fighting addiction would focus a lot on assisting the Center for Disease Control and Prevention (CDC). This week the opioid commission’s statement calling for the President’s immediate action states:
“Our citizens are dying. We must act boldly to stop it. The first and most urgent recommendation of this Commission is direct and completely within your control. Declare a national emergency.”
While insisting that the administration put forth an emergency declaration, the specially appointed opioid commission said that Trump is the-
“-only person who can bring this type of intensity to the emergency and we believe you have the will to do so and to do so immediately.”
The opioid commission was deliberate in the details, acknowledging that with 142 Americans dying every day from drug overdoses-
“America is enduring a death toll equal to September 11th every three weeks.”
When you think about it in this context, the statistics become even more startling and horrifying. The fact that so many men, women and even children in America are losing their lives to drugs like heroin and prescription pain medication. The opioid commission went on to say:
“Your declaration would empower your cabinet to take bold steps and would force Congress to focus on funding and empowering the Executive Branch even further to deal with this loss of life,”
“It would also awaken every American to this simple fact: If this scourge has not found you or your family yet, without bold action by everyone, it soon will.”
In the last few months there has been some waves of criticism against the opioid commission after missing two deadlines to release this report in June and July. Now that the report is finally here, what can be done to address the concerns the opioid commission brings with it?
Will the White House Take Action?
According to initial reports the White House intends to “immediately” review the recommendations of the opioid commission. In the statement from the White House:
“The opioid crisis is a tragedy that has been harming America’s communities for far too long. We appreciate the Commission’s hard work on this important interim report. We will immediately begin reviewing its recommendations, and eagerly await its final report.”
The final report from the opioid commission is expected to be submitted during October. Still, many are hoping the Trump administration does not wait that long to start planning for a response.
The opioid commission made many recommendations in the interim report for efforts to curb the opioid epidemic and the increasingly high death rates. Those recommendations include:
- Rapidly increase treatment capacity for those who need substance abuse help
- Establish and fund better access to medication-assisted treatment programs
- Make sure that health care providers are aware of the potential for misuse and abuse of prescription opioids by enhancing prevention efforts at medical and dental schools
- Equipping all law enforcement in the United States with naloxone to save lives
Naloxone is the opioid overdose antidote used by first responders to save people overdose victims. So far access to Naloxone and Narcan, the name brand, has expanded, but many think not nearly enough.
With the fight for healthcare in Congress seeming to hit every rough patch possible on the road to settling on legislation, people are already worried about how coverage may or may not change for tens of millions of Americans. So the concern for how to face a growing addiction problem while simultaneously afflicted with a potential healthcare crisis is very real for a lot of people.
Time will tell if the Trump administration acts on the suggestion to declare a state of emergency to call more action toward the opioid epidemic. And if they do declare it, what will change?
Palm Healthcare Company Offering Holistic Health
While Palm Healthcare Company is not qualified to fix all the problems in politics, we do believe in providing quality care to as many men and women struggling as possible. Palm Healthcare Company facilities create a safe, comfortable and effective environment to experience powerful and life-changing courses and treatments focused on holistic health.
While the opioid epidemic may not be an easy issue to solve, Palm Healthcare Company believes in helping those who have suffered from addiction to opioids and/or other drugs find a new way and a second chance. With medical detox, personalized inpatient and outpatient treatment options and aftercare opportunities such as Recovery Coaching, Palm Healthcare Company wants to support every part of your journey.
Overcoming the opioid epidemic means helping those who have suffered heal.
Drug abuse and addiction is a devastating and deadly disease, and providing effective and compassionate treatment makes a lifelong difference. If you or someone you love is struggling with substance abuse or addiction, think about who you want to be working with to find a real solution. Please call toll-free now.
CALL NOW 1-888-922-5398
by Justin Mckibben | Jul 27, 2017 | Drug Abuse, Heroin, Maintenance Drugs, Opioids, Prescription Drugs, Vivitrol
(This content is being used for illustrative purposes only; any person depicted in the content is a model)
Opioid and heroin addiction is without a doubt one of the most unrelenting public health issues we as a country are facing today. Overdose death rates continue to risk to staggering heights, while politicians, community leaders and organizations all over America are working to find a way out. One of the companies that produces the lifesaving opioid overdose antidote Narcan is talking about their efforts to develop an opioid vaccine.
This isn’t the first time there has been a conversation about possible opioid vaccines. Naltrexone, also known by the brand name Vivitrol, was initially used for combatting alcohol dependence before being utilized in attempt to combat opioid abuse.
A while back in 2015 Kim Janda, a professor at the Scripps Research Institute created a compound he believed could ultimately be used as a heroin vaccine. Since then the research team has made some impressive strides in achieving their goal. The experts from the Virginia Commonwealth University and the Scripps Research Center discovered that the vaccine, which was the first of its kind to reach this phase of preclinical testing, was effective on rhesus macaques, a species of monkeys. This vaccine generates antibodies that neutralize heroin’s psychoactive metabolite and prevents it from acting on the opioid receptors in the brain.
So will this new opioid vaccine be the real deal?
Opioid Vaccine from Walter Reed
On a FOX News segment this past Wednesday, Dr. Mark Siegel, spoke about a new compound coming from the Walter Reed Army Institute of Research (WRAIR) and the NIH’s National Institute on Drug Abuse (NIDA. Dr. Siegel said he was happy to hear it was coming from Walter Reed because of the large issue with opioid drug use among veterans. According to Siegel:
“It uses antibodies to attack heroin or Percocet, or Vicodin; anything like that that’s an opioid, literally you make antibodies. So if it’s in your bloodstream it can’t get to the brain. It doesn’t cause you to stop breathing so you don’t overdose and you don’t have the euphoric feeling.”
According to the interview with Siegel, someone would hypothetically be able to go to a doctor, get inoculated and the opioid vaccine would create antibodies to block the effects of heroin and other opioids.
Dr. Siegel did say that it may end up being a substance that has to be administered periodically. He states human trials with the opioid vaccine have apparently only just started, but animal trials thus far seem to have been very promising.
Dr. Siegel goes on to say that once the opioid vaccine has been administered, the possibility is one could potentially be prescribed another opioid maintenance drug like Suboxone in order to taper off of opioids while not being able to feel the effects of opioids.
Dr. Siegel admits that there is still a lot of testing that needs to be done before the drug can be approved by the FDA, but he believes if the opioid vaccine is successful it could change the entire epidemic.
Opiant Jumps on Opioid Vaccine
A Big Pharma company known for their opioid overdose antidote announced back in late 2016 that they had acquired exclusive development and commercialization rights to the pre-clinical heroin vaccine. CEO of Opiant Pharmaceuticals, Dr. Roger Crystal, said in a recent statement:
“Aggressively addressing heroin addiction is part of Opiant’s mission… This vaccine fits our plan to develop innovative treatments for this condition. The vaccine has promising preclinical data.”
The Opiant Pharmaceuticals aspiration is also to create a compound that blocks the effects of opioid drugs like heroin. Dr. Crystal also said that they would like to develop their own version of the Naltrexone implant as a long-term opioid blocker.
Opiant also says that if further preclinical testing of the opioid vaccine is successful, the company plans to team up with WRAIR researchers in the U.S. Military HIV Research Program to eventually combine the HIV vaccine with the potential heroin vaccine, making a huge leap in the direction of fighting back against two of the biggest issues concerning the opioid epidemic.
Would Opioid Vaccine Work?
The bigger question we keep having to ask when talking about the concept of an opioid vaccine- will it work? Not saying that the vaccine won’t be effective at blocking the brains opioid receptors, but is this an effective strategy to combatting addiction?
One question I would think to ask is will addicts who are trying to overpower the vaccine end up taking even more of the drugs until they suffer other severe health complications. Is blocking the opioid receptors a comprehensive way of protecting people from overdosing on opioids? Which opioids would still be extremely dangerous? Will this work on drugs like fentanyl or carfentanil?
Beyond that, the question also becomes- will addicts quit, or will they use something else? If many can substitute their addiction with another substance, will a opioid vaccine make other drugs more popular?
Only more time and more research will show us how effective the new opioid vaccine could be to helping end the opioid epidemic in America. Right now with statistics being as serious as they are, any avenue that has real potential to save lives should be pursued.
Then I have to ask- with many Big Pharma companies that make Narcan and other opioid antidotes jacking up their prices, will Opiant and other vaccine makers use the miracle drug to exploit the desperation of the epidemic with intense prices?
There is no miracle cure for opioid or heroin addiction yet, but it seems many have not given up hope of finding one. What we do have today is safe and effective treatment options that offer unique opportunities to change your life. If you or someone you love is struggling with substance abuse or addiction, please call toll-free now.
CALL NOW 1-888-922-5398
by Justin Mckibben | Jul 11, 2017 | Drug Abuse, Opana, Opioids, Prescription Drugs
Oxymorphone is a powerful semi-synthetic opioid analgesic developed in Germany back in 1914. Since the painkiller’s introduction into the medical world it has gone by many brand names, such as:
-
Numorphan (suppository and injectable solution)
-
Opana ER (extended-release tablet)
-
Opana IR (immediate-release tablet)
-
O-Morphon in Bangladesh by Ziska pharmaceutical ltd
In the midst of the opioid epidemic in America many pharmaceutical drugs are now under close scrutiny for their addictive potential. Now, a public announcement has come to light explaining that in June of 2017, the U.S. Food and Drug Administration asked the manufacturer of Opana ER, a Oxymorphone medication, to remove the product from the market.
What is Opana?
Opana or Oxymorphone is meant for use as:
- Moderate to severe pain relief
- Preoperative medication to alleviate apprehension
- Medication to maintain anaesthesia
- As a obstetric analgesic
Oxymorphone extended-release tablets are designated for managing chronic pain. These tablets are also only for people already on a regular schedule of strong opioids for an extended time.
Oxymorphone immediate-release tablets are recommended for breakthrough pain for people on the extended-release version.
Endo International PLC is the Big Pharma empire based in Dublin, Ireland that manufactures Opana.
- 2006- Opana approved for use in the United States
- 2012- Endo changed the drug’s formulation to try to make it harder to abuse. The FDA approved sales of the new version, however the FDA prohibited Endo International from marketing Opana as abuse deterrent.
- 2013- the Centers for Disease Control and Prevention (CDC) reported an illness associated with intravenous abuse of oral Opana ER in Tennessee.
- 2015- Reports in Austin, Indiana indicated an outbreak of HIV was caused by recreational injection of Opana
Endo primarily makes generic medicines, as well as a number of brand-name specialty drugs. Endo reported that Opana ER last year posted net sales of $159 million.
Opana ER Abuse
The FDA has taken a revolutionary stance after deciding that the risks greatly outweighed the benefits of Opana use.
In a statement on Thursday Endo International PLC said it will voluntarily stop selling the pills. However, the drug-maker does not necessarily agree with the conclusion made by the FDA, adding in their statement that the extended-release opioid is safe and effective when used as intended, and that Endo still believes Opana ER’s benefits outweigh its risks.
And yet, FDA advisers are firm after reviewing the safety of Opana ER and voting 18-8 against keeping it on the market.
The agency said it had perceived a “significant shift” from individuals abusing the drug recreationally by crushing and snorting the pill to injecting it instead. Besides the stories in Indiana and Tennessee, Opana was also called out for contributing to the rising rates of drug overdose and overdose deaths.
According to the FDA there were no generic versions of the reformulated Opana ER on the market, as of June. However, there are two generics of earlier versions of Opana on sale, called Oxymorphone.
The Big News For Big Pharma
The big news here is that this is the first time the U.S. Food and Drug Administration has actively taken steps to remove a currently marketed opioid pain medication from sale due to the drugs abuse and the related public health consequences!
Some see this as a major move in the fight toward overcoming the opioid addiction problem gripping the nation.
Thus, Endo International PLC has committed to working with the FDA to try to minimize disruption for patients relying on the drug for pain relief. Of course those prescribed to the drug for medical reasons will also need to be provided with alternative treatments.
But the FDA isn’t done yet. The U.S. Food and Drug Administration claims that its agencies will be reviewing other opioid painkillers and could take further action to regulate or even eliminate dangerous opioid medications like Opana ER.
Taking steps to reduce the impact of this epidemic is a step in the right direction. Big Pharma might be in for a bit of a shakedown from the FDA as they attempt to reduce the amount of dependence on opioids. If you or someone you love is struggling, please call toll-free now.
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