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Opioid Vaccine Being Developed by Narcan Drug Makers

Opioid Vaccine Being Developed by Narcan Drug Makers

(This content is being used for illustrative purposes only; any person depicted in the content is a model)

Opioid and heroin addiction is without a doubt one of the most unrelenting public health issues we as a country are facing today. Overdose death rates continue to risk to staggering heights, while politicians, community leaders and organizations all over America are working to find a way out. One of the companies that produces the lifesaving opioid overdose antidote Narcan is talking about their efforts to develop an opioid vaccine.

This isn’t the first time there has been a conversation about possible opioid vaccines. Naltrexone, also known by the brand name Vivitrol, was initially used for combatting alcohol dependence before being utilized in attempt to combat opioid abuse.

A while back in 2015 Kim Janda, a professor at the Scripps Research Institute created a compound he believed could ultimately be used as a heroin vaccine. Since then the research team has made some impressive strides in achieving their goal. The experts from the Virginia Commonwealth University and the Scripps Research Center discovered that the vaccine, which was the first of its kind to reach this phase of preclinical testing, was effective on rhesus macaques, a species of monkeys. This vaccine generates antibodies that neutralize heroin’s psychoactive metabolite and prevents it from acting on the opioid receptors in the brain.

So will this new opioid vaccine be the real deal?

Opioid Vaccine from Walter Reed

On a FOX News segment this past Wednesday, Dr. Mark Siegel, spoke about a new compound coming from the Walter Reed Army Institute of Research (WRAIR) and the NIH’s National Institute on Drug Abuse (NIDA. Dr. Siegel said he was happy to hear it was coming from Walter Reed because of the large issue with opioid drug use among veterans. According to Siegel:

“It uses antibodies to attack heroin or Percocet, or Vicodin; anything like that that’s an opioid, literally you make antibodies. So if it’s in your bloodstream it can’t get to the brain. It doesn’t cause you to stop breathing so you don’t overdose and you don’t have the euphoric feeling.”

According to the interview with Siegel, someone would hypothetically be able to go to a doctor, get inoculated and the opioid vaccine would create antibodies to block the effects of heroin and other opioids.

Dr. Siegel did say that it may end up being a substance that has to be administered periodically. He states human trials with the opioid vaccine have apparently only just started, but animal trials thus far seem to have been very promising.

Dr. Siegel goes on to say that once the opioid vaccine has been administered, the possibility is one could potentially be prescribed another opioid maintenance drug like Suboxone in order to taper off of opioids while not being able to feel the effects of opioids.

Dr. Siegel admits that there is still a lot of testing that needs to be done before the drug can be approved by the FDA, but he believes if the opioid vaccine is successful it could change the entire epidemic.

Opiant Jumps on Opioid Vaccine

A Big Pharma company known for their opioid overdose antidote announced back in late 2016 that they had acquired exclusive development and commercialization rights to the pre-clinical heroin vaccine. CEO of Opiant Pharmaceuticals, Dr. Roger Crystal, said in a recent statement:

“Aggressively addressing heroin addiction is part of Opiant’s mission… This vaccine fits our plan to develop innovative treatments for this condition. The vaccine has promising preclinical data.”

The Opiant Pharmaceuticals aspiration is also to create a compound that blocks the effects of opioid drugs like heroin. Dr. Crystal also said that they would like to develop their own version of the Naltrexone implant as a long-term opioid blocker.

Opiant also says that if further preclinical testing of the opioid vaccine is successful, the company plans to team up with WRAIR researchers in the U.S. Military HIV Research Program to eventually combine the HIV vaccine with the potential heroin vaccine, making a huge leap in the direction of fighting back against two of the biggest issues concerning the opioid epidemic.

Would Opioid Vaccine Work?

The bigger question we keep having to ask when talking about the concept of an opioid vaccine- will it work? Not saying that the vaccine won’t be effective at blocking the brains opioid receptors, but is this an effective strategy to combatting addiction?

One question I would think to ask is will addicts who are trying to overpower the vaccine end up taking even more of the drugs until they suffer other severe health complications. Is blocking the opioid receptors a comprehensive way of protecting people from overdosing on opioids? Which opioids would still be extremely dangerous? Will this work on drugs like fentanyl or carfentanil?

Beyond that, the question also becomes- will addicts quit, or will they use something else? If many can substitute their addiction with another substance, will a opioid vaccine make other drugs more popular?

Only more time and more research will show us how effective the new opioid vaccine could be to helping end the opioid epidemic in America. Right now with statistics being as serious as they are, any avenue that has real potential to save lives should be pursued.

Then I have to ask- with many Big Pharma companies that make Narcan and other opioid antidotes jacking up their prices, will Opiant and other vaccine makers use the miracle drug to exploit the desperation of the epidemic with intense prices?

There is no miracle cure for opioid or heroin addiction yet, but it seems many have not given up hope of finding one. What we do have today is safe and effective treatment options that offer unique opportunities to change your life. If you or someone you love is struggling with substance abuse or addiction, please call toll-free now.

CALL NOW 1-888-922-5398

Why South Florida Is Still Great For Addiction Treatment

Why South Florida Is Still Great For Addiction Treatment

Recently I came across an article with a title essentially warning people not to send their family members to Florida for drug and alcohol treatment. The interviews argue that high rates of overdose should justify officials urging people in other states not to send their kids to treatment in the area. However, the article also acknowledges that “South Florida has long been a destination for world-class addiction treatment” and includes a quote from Palm Beach County League of Cities member Andy Amoroso stating:

“Stop sending your children and your loved ones to South Florida,”

I think there is a real problem with this kind of statement though…

It ignores the fact that most people looking for recovery come from states with much worse issues of overdose crisis than South Florida. 

To be clear, Florida has seen a spike in drug related issues, but guess what… so has basically everywhere in America! We are in the midst of a drug overdose epidemic all across this nation.

For example, let’s talk about where I came from. In 2014 I wrote about how my home state of Ohio led the nation in opioid overdose deaths. Ohio now also has the highest rates of heroin related deaths.

1 out of every 9 heroin deaths… happens in Ohio!

Dayton, Ohio is number 1 in the country by many reports for drug overdoses. Today, Dayton is quickly becoming known as the heroin capitol of America.

I have lived in Florida for around 4 years after coming to Delray Beach to get sober. I am an active member of a vast recovery community in the Palm Beach County area, and I would never have gotten the chance to do all the amazing and life changing work I am privileged to do if no one had sent me to South Florida to get help. In all likelihood, I would be dead.

Crunching the Country’s Overdose Numbers

There is no denying that Florida is typically in the top 5 rankings when it comes to total overdose numbers. However, there should also be some context to really show the difference between how other states are being affected. To get a little perspective, I want to run down some numbers.

The Henry J. Kaiser Family Foundation compiled data from every state in order to show some details on the opioid overdose crisis. In those numbers they discovered the top 3 states in opioid overdose deaths for 2014 were:

  1. Ohio- 2,106 opioid overdoses- which was 7.4% of nationwide deaths

  1. California- 2,024 deaths

  1. New York- 1,739 deaths

Out of 10,584 nationwide heroin related deaths in 2014, 1,208 were in Ohio. That is 11.4% of the countries heroin deaths in a state with a population a fraction of the size of California’s, New York’s and Florida’s.

In 2015 the top 3 states for overall overdoses were:

  1. California- 4,659

  2. Ohio- 3,310

  3. Pennsylvania- 3,264

In 2015 Ohio’s overdose death rates jumped again to 3,310. In 2016 those numbers are again expected to have skyrocketed to well over 4,000.

While we should acknowledge that the entire state of Florida had around 3,228 overall overdose deaths in 2015, Florida actually had less deaths per 100,000 people compared to 23 other states! These numbers include the top 5:

  1. West Virginia- 41.5 per 100,000 people

  2. New Hampshire- 34.3 per 100,000 people

  3. Kentucky- 29.9 per 100,000 people

  4. Ohio- 29.9 per 100,000 people

  5. Rhode Island- 28.2 per 100,000 people

As well as:

  • Michigan

  • Massachusetts

  • Tennessee

  • Maryland

  • Indiana

  • Louisiana

  • Connecticut

  • Oklahoma

  • New Mexico

  • Nevada

  • Arizona

  • Utah

  • Maine

  • Delaware

  • Missouri

  • Vermont

  • Wyoming

  • New Jersey

So while Florida may be experiencing high rates of overdose, we need to see that dozens of states are seeing a much higher percent of their population be killed by drugs. Some states have less than half the population Florida does, but are still suffering with tragically high percentages of their population dying from overdose. Those people who want help deserve access to that same “world-class addiction treatment” that South Florida has to offer. For several years, countless families across the U.S. have suffered while the resources and the community in South Florida has helped to save thousands of men and women who needed a little hope and a second chance.

Prescription Drug Problem

In the Midwest, the problem with prescription drug abuse is an extremely distressing element of the opioid crisis. In 12 states, the number of opioid painkiller prescriptions actually exceeds the number of residents living in those states! This includes:

  • New Hampshire

Out of the 1.3 million people living in this state, there were 13 million doses of opioids dispensed in a 3 month period!

  • West Virginia

  • Oklahoma

  • Arkansas

  • Louisiana

  • Alabama

  • Tennessee

  • Mississippi

  • South Carolina

  • Kentucky

  • Michigan

  • Ohio

Just in case you haven’t seen the news in the past few years, prescription drugs have been one of the largest contributing factors to the current opioid epidemic and the rise in heroin addiction.

Real Resources

The reality is professional and effective treatment programs in South Florida save the lives of countless people from all over the United States. The positive impact on the world is immeasurable. The reason so many people travel here for treatment is not just the fact that there are beaches and sun in Florida (Although they are amazing). They travel because so many of the states being hit the hardest by the opioid epidemic are states that have limited resources when it comes to comprehensive drug addiction treatment.

We aren’t traveling here to bring drugs Florida had never heard of before. We’re trying to escape the familiar and fatal atmosphere we were stuck in for so long. We take this drastic step in a desperate time because we want to believe the help is out there.

Some would still argue that a large number of treatment centers creates a problem with corruption within the industry itself. One can’t argue with some of the stories we read, but if that’s the case maybe instead of turning people away we should be educating people on the most important things to look for in a legitimate treatment program. We should encourage families to seek out qualified and established addiction specialists. Instead of insisting they shouldn’t trust the industry; we should be telling them to look for the accredited addiction specialists who have earned a respected reputation through their record in service and their certifications. Let’s celebrate the treatment providers who do make a difference instead of signing on for whole-sale condemnation.

At the very least, lets teach them to make sure a treatment facility in South Florida is approved by:

  • The Joint Commission

The Joint Commission is a United States-based nonprofit organization that accredits more than 21,000 health care organizations and programs in the U.S.

  • Florida Department of Children and Families (DCF)

The DCF is a state agency providing social services to children, adults, refugees, domestic violence victims and a number of other groups.

To learn more about how to find an accredited and effective treatment program, download our FREE e-book

“5 Critical Mistakes When Picking a Treatment Center and How to Avoid Them”

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No matter where we live we should never turn people away from our community for help. We should provide a platform for awareness. It is critical that addicts and their families know what makes effective treatment programs important. Florida should always be proud of the strength of its recovery community.

We are in this together

Accurate and detailed data for overdose death rates 2016 is not yet available. Yet it is estimated that almost 60,000 Americans died last year from drug overdose. Some experts say over 2 million Americans are suspected to be opioid dependent currently, and that overdose death rates in 2017 are only going to get worse.

Of course, it is understandable that people are concerned about the strain that addiction and overdose puts on their communities, but there is something we cannot, as Americans, forget… we are in this together. In the article I mentioned previously, one of the individuals quoted spoke of people struggling with addiction like we are all inconvenient intruders who have no place in their neighborhood. Thankfully, this is not the experience many of us live with.

I have to say it again… We are in this together.

We are all citizens of the same free country fighting the same fight. Even more important, we are all human beings. Every one of us is free to seek something that can save us. I often believe I would have never had this chance if I had not come to South Florida. I didn’t know what was possible… and thankfully nobody told me not to come looking for it. Nobody told me I wasn’t welcome.

This isn’t just about South Florida; any community with addiction treatment programs and a recovery community should know, we get it. We understand how it can seem a little scary when you think your neighborhood is changing. It’s easier to say “as long as it’s happening over there” until “over there” becomes everywhere.

At the height of the opioid epidemic in America, it is certainly not the time to hide the welcome mat and use fear to scare people away. It is time to make our voices louder and unify the recovery community to show more people that recovery is possible. Until more treatment opportunities are advocated for across the country, we will use every resources we have to preserve and protect the lives of those who are suffering. South Florida is still a great place for addiction treatment. If no one has told you yet, you are welcome here!

Palm Healthcare Company has been serving the South Florida community for 20 years, now with multiple specialized facilities and innovative holistic treatment programs designed to help create lasting change. If you or someone you love is struggling with substance abuse or addiction, please call now. We want to help. You are not alone.

CALL NOW 1-888-922-5398

What Is A Methadone Clinic?

What Is A Methadone Clinic?

Ever since Methadone was introduced to combat opioid dependence, it has been leaned on by countless people over several decades to treat opioid abuse. For a long time methadone clinics have been looked to as a source of relief from an addiction to opioids, but are they as effective as people seem to think? Over time more people who have used methadone to try overcoming serious addictions have realized methadone maintenance also comes with a great deal of damaging side effects.

What is a methadone clinic?

A methadone clinic is a clinic for the dispensing of methadone. Because this is a schedule II opioid analgesic drug, access must be restricted. Methadone clinics are a way to provide people with this medication. But before you rush out to find the one closest to you, there are a lot of things to consider.

What is a Methadone Clinic: History of Methadone

Firstly, let us not that methadone is an opioid drug. It is used to treat pain, like most opioid medications, but most people know it as a maintenance drug for detoxing from dependence on other opioids, such as heroin. Methadone, sold under many brand names, including:

  • Methadose
  • Dolophine
  • Symoron
  • Amidone
  • Physeptone
  • Diskets

Different countries have different brands as well. A few footnotes of the history of methadone include:

  • 1937 to 1939

Methadone was developed in Germany by Gustav Ehrhart and Max Bockmühl.

  • 1947

The United States approved the use of Methadone.

  • 2013

About 41.400 kilograms of methadone were manufactured globally

What is a Methadone Clinic: Methadone Detox

Methadone is available in various forms, including:

  • Pill
  • Sublingual tablet
  • Two different formulations designed for the patient to drink

Drinkable forms include:

  • Methadose- the ready-to-dispense liquid form found in theUnited States.
  • Diskets- tablets designed to work like Alka-Seltzer, dispersing rapidly in water for oral administration.

The most common method of administration is the liquid form, because it allows for small dose changes. Methadone is almost as effective when administered orally as by injection.

Detoxification using methadone is intended to be a way for people addicted to opioids such as heroin or powerful prescription drugs to taper off, but at the same time detoxification using methadone has been met with a great deal of controversy.

Many who oppose methadone clinics refer to this strategy as methadone substitution. As a treatment of opioid addiction methadone is heavily criticized for its role in what some call “social control of addicts.” Many who oppose methadone suggested that the drug does not function as much to curb addiction as to redirect it and maintain dependency. In other words, some insist methadone is essentially keeping people addicted, but making sure the money goes to drug manufactures and methadone clinics instead of street dealers.

What is a Methadone Clinic: Methadone Side-Effects

There are so many adverse effects of methadone, which may vary in range and severity depending on the individual. There include, but are not limited to:

  • Sedation
  • Diarrhea or constipation
  • Perspiration
  • Heat intolerance
  • Dizziness
  • Fainting
  • Itching
  • Weakness
  • Chronic fatigue
  • Sleep problems
  • Nausea
  • Hallucinations
  • Memory Loss
  • Weight gain
  • Stomach pains
  • Mood changes
  • Restlessness
  • Decreased libido or impotence
  • Urinary difficulty
  • Blurred vision
  • Skin rash
  • Low blood pressure
  • Headaches
  • Seizures
  • Heart problems
  • Respiratory problems

Some of these adverse effects of methadone use are much more serious than others.

What is a Methadone Clinic: Withdrawal Symptoms

There is also a massive list of possible withdrawal symptoms from using methadone. This is one of the primary issues many people have with methadone treatment.

Physical withdrawals include:

  • Runny nose and sneezing
  • Nausea
  • Vomiting
  • Diarrhea
  • Fever
  • Sweating
  • Chills
  • Aches and pains (especially in joints)
  • Sensitivity to pain
  • Hyperventilation
  • Tremors
  • High blood pressure that may cause strokes

Others are more concerned with the mental aspect of the withdrawals experienced from methadone.

Cognitive withdrawals include:

  • Suicidal ideation
  • Drug cravings
  • Depression
  • Insomnia
  • Delirium
  • Hallucinations (auditory and visual)
  • Agitation
  • Anxiety
  • Panic disorder
  • Paranoia
  • Delusions
  • Apathy

The irony is that methadone withdrawal symptoms are even reported to last significantly longer than withdrawals from some other opioids. In some cases, people may even try to treat an opioid addiction with this drug not knowing that it is actually a much worse opioid to withdrawal from.

What is a Methadone Clinic: Methadone Overdose

As mentioned before, there are some very real dangers when it comes to using methadone.

  • Between 1999 and 2004, deaths in the U.S. linked to methadone quadrupled.
  • In 2004 reports credit methadone as contributing to 3,849 deaths, 82% of which were reported as accidental.
  • In 2011, there were 4,418 deaths in the United States involving methadone. At the time that made up 26% of total deaths fromopioid poisoning.

Respiratory depression is probably the most common overdose risk related to opioid drugs. Other symptoms of a methadone overdose include:

  • Hypoventilation (slow/shallow breathing)
  • Drowsiness
  • Cool, clammy skin
  • Limp muscles
  • Unconsciousness
  • Coma
  • Excessive vomiting
  • Risks are greater with higher doses, as well as mixing methadone with any other drugs.

The risks of methadone are very, very real. In fact, U.S. Food and Drug Administration (FDA) issued a Public Health Advisory back in 2006 about methadone titled “Methadone Use for Pain Control May Result in Death and Life-Threatening Changes in Breathing and Heart Beat”. In the report, the FDA stated that they received reports of death and life-threatening side effects with patients who were newly starting methadone.

Both individuals who were starting methadone for pain, or who were trying to switch to it from another powerful narcotic pain reliever were included to be at an elevated risk, according to the FDA.

What is a Methadone Clinic: Another Way

Getting off of powerful opioid drugs, whether they are prescription narcotics or illicit street drugs, is possible without the use of methadone. While maintenance drugs can be useful to some extent as a means of harm reduction, these should not be considered as sustainable means of addiction recovery. Maintenance drugs are typically only ever effective if utilized in combination with therapy and other forms of addiction treatment.

Luckily there are other ways to get help. It is possible to be safely and effectively removed from a methadone taper through a safe medical detox. Understanding methadone can also be fatal is of vital significance. Methadone detox can be deadly if not supported by a medical staff with the right medications to help ease the pain and discomfort of the detox. Medical detox combined with a holistic treatment program is a proven strategy for saving lives.

If you or someone you love is struggling, do not wait. Please call toll-free now. We want to help. You are not alone.

CALL NOW 1-888-922-5398

Public Bathrooms Become Ground Zero in the Opioid Epidemic

Public Bathrooms Become Ground Zero in the Opioid EpidemicPublic bathrooms are ground zero in the opioid epidemic, according to a recent report. Addicts like Eddie* know all about this. In an interview with NPR, Eddie declares every single bathroom in Cambridge, Massachusetts that he among many others uses to get high.

“I know all the bathrooms that I can and can’t get high in,” says Eddie, 39, in the interview.

“With these bathrooms here, you don’t need a key. If it’s vacant, you go in. And then the staff just leaves you alone,” Eddie says. “I know so many people who get high here.”

Even at fast food places, Eddie has his technique for gaining access.

“You don’t need a key, but they have a security guard that sits at the little table by the door, directly in front of the bathroom,” Eddie says.

“Some guards require a receipt for admission to the bathroom,” he says, “but you can always grab one from the trash.”

*Name Changed

Managing Public Bathrooms is ‘Tricky.’

Businesses in the area struggle to come up with solutions to the problem. Some have installed low lighting, blue in particular, to make it difficult for users to find a vein.

The city of Cambridge plans to install “Portland Loos” in the heart of Central Square by the end of the summer.  The “Portland Loo” public bathrooms originated in the city of Portland, Organ. These toilets reduce privacy and ensure police can see in if they suspect illegal activity.

Furthermore, the Loos have:

  • No running water inside: Prevents people from using the water to clean themselves.
  • No mirror: People tend to smash mirrors.
  • Bars at the top and bottom of the structure: This reduces privacy. Cops can peep in near the ground to make sure there’s no more than one set of feet inside.  Furthermore, you hear sounds inside and outside of the bathrooms. Nobody wants to stick around these toilets for long.
  • A graffiti-proof coating: No one will be tagging these bathrooms.
  • Walls and doors made from heavy-gauge stainless steel

Business owners hope that these bathrooms will relieve pressure on their bathrooms. However, others worry they will become a haven for drug use.

The bathrooms at 1369 Coffee House in Central Square are open for customers who request the code from staff at the counter. Owner Joshua Gerber required this step to make the bathrooms safer. He also installed metal boxes in the mall next to his toilet for needles and other things that clog pipes.

“We’d find needles or people’s drugs,” Gerber says to NPR. “It’s a tricky thing, managing a public restroom in a big, busy square like Central Square where there’s a lot of drug use.”

In recent years, Geber and his staff have found several people lying on the bathroom floor unconscious.

“It’s very scary,” Gerber says. “In an ideal world, users would have safe places to go that it didn’t become the job of a business to manage that and to look after them and make sure that they were OK.”

Safe Needle Exchange Programs?

In the past, we have mentioned areas in Canada and some European Countries that offer safe areas to do drugs. The United States is slowly coming around to providing these facilities as well.  Though controversial, these safe needle injection sites offer a place for addicts to use drugs and reduce overdose fatalities. They also reduce crime and will hopefully reduce drugs done in public restrooms.
The city of Las Vegas plans to decrease the risk of sharing contaminated needles by installing vending machines throughout the city.  These vending machines would provide clean needles to addicts reducing infectious diseases. They would also offer disposal containers to dispose of needles safely. This would prevent needles from being disposed of improperly.

Officials in several states in America have proposed the implementation of supervised injection facilities, including:
  • New York
  • California
  • Washington D.C.

Supervised injection facilities (SIFs) are legally sanctioned locations where people who use intravenous drugs can inject pre-obtained drugs under medical supervision. There are pros and cons to these facilities, however, they are likely to reduce drug sue on the streets and reduce infections from needle sharing. Furthermore, they reduce overdose fatalities.

Limits on Discussion and Direction

Overall, discussions on safety practices for bathrooms remain sparse. There is a reason why:

“It’s against federal and state law to provide a space where people can use knowingly, so that is a big deterrent from people talking about this problem,” says Dr. Alex Walley, director of the addiction medicine fellowship at Boston Medical Center.

Still, without guidance, many libraries, town halls, and businesses are shutting their bathrooms down to the public. Closing down public restrooms leads to more drug use, injuries and discarded needles on the streets and in parks with children playing.

There are a variety of methods that could make bathrooms safer for the public and drug users.

  • A model restroom would be clean and well-lit and have very few cracks and crevices for hiding drug paraphernalia.
  • Bathrooms should also contain a biohazard box for needles and bloodied swabs.
  • These bathrooms would also need naloxone and perhaps sterile water.
  • The door with open out so a collapsed body would not block entry.
  • It would need to be easy for EMTS and authorizes to unlock from the outside in the case of an emergency.

Very few bathrooms meet these standards in the United States. Sadly, as the opioid epidemic continues to take lives each and every day, these issues must be addressed. How can cities improve the safety of their public bathrooms?

Doctors, nurses and public health workers who help addiction patients every day argue the solution will have to include safe injection sites.

If communities like Boston start to reach a breaking point with bathrooms, “having dedicated facilities like safer drug consumption spaces is the best bet for a long-term structural solution that I think a lot of business owners could buy into, “ says Daniel Raymond. Raymond is deputy director of policy and planning at the New York-based Harm Reduction Coalition.


No business groups in Massachusetts have come out for such spaces yet. Time will tell what changes occur. Getting the right kind of treatment for drug addiction is paramount to progress. If you or someone you love is struggling, don’t wait. Please call toll-free now.

CALL NOW 1-888-922-5398

How Long Does Heroin Stay in Your System?

How Long Does Heroin Stay in Your System?

Heroin (diacetylmorphine) is a Schedule I controlled-substance in the United States and is considered by many to be the most addictive drug in the world when compared to other more popular illicit drugs. Heroin is typically associated with the highest likelihood of developing an addiction both psychologically and physically.

Given the fact that the country is facing the most deadly drug epidemic in American history thanks to the opioid overdose outbreak, heroin abuse is now a primary concern facing most of the nation. Other opioids, like prescription painkillers, have contributed to the rising rates of heroin use, and the addition of other potent drugs like fentanyl, heroin is more dangerous than ever.

Heroin overdose is currently one of the top causes of accidental death. People use more than the body can handle and it shuts down. Also, the withdrawals of heroin can be particularly difficult. So how long does heroin stay in your system?

How Long Does Heroin Stay in Your System: Important Elements

When asking how long does heroin stay in your system we have to examine some of the important elements that impact the effects of heroin on the body. Heroin is typically injected intravenously to make a faster impact, but it is also smoked or snorted. Heroin has longer lasting effects compared to drugs like cocaine and meth, but it also has a shorter half-life of only approximately 30 minutes.

What does half-life of heroin mean? Essentially, when an individual uses a single dose of heroin, it will take about 30 minutes for half of the drug in the person’s system to be flushed out. However, some studies actually suggest that this half-life is as short as 3-8 minutes, not 30.
The accurate amount of time it would take is not cut and dry. The half-life of heroin depends on a number of factors for each individual, including:

  • Height
  • Weight
  • Age
  • Genetics
  • Body fat
  • The amount taken
  • Purity of the drug
  • Method of use
  • Metabolism
  • Health of the liver
  • Kidney health
  • Hydration

Not all bodies are the same, so of course not all bodies will be able to get rid of heroin at the same exact rate. A body with more fatty tissue and less hydration will probably retain the chemicals longer than someone well-hydrated with a lean build.

How Long Does Heroin Stay in Your System: Drug Testing for Heroin

Some might hope they can measure the presence of heroin in the system based on drug tests. Of course the length of time a drug is detectable with a drug test depends directly on the rate at which heroin leaves the body. Different drug tests often have different lengths of time they measure, so one might be able to tell you someone used heroin, but it may not be particularly active in the body.

Approved drug tests through the Food and Drug Administration (FDA) for heroin use:

  • Blood
  • Saliva
  • Urine
  • Hair follicle

Heroin is typically no longer detectable in a person’s urine after just 2 days, but some tests have detected positive results in up to 7 days.
Blood and saliva tests aren’t often used for most opioids because they have such a short half-life. It can only take about 5-6 hours for heroin to be undetectable for these tests, but in some cases it may actually last up to 2 days.

The only effective long-term test for traces of heroin is the hair follicle test, which can detect heroin for up to 3 months or more. However, if you are trying to find out if heroin is still active in the body, the long-term doesn’t really help.

Many tests now look for heroin metabolites, which are what is created when the liver metabolizes the drug. These stay in the system much longer than the actual intoxicant, so while you can detect the presence of the metabolites, the drug itself isn’t necessarily active. However, many believe that among long-term and/or frequent heroin users, the drug may actually remain in a person’s system for much longer than detectable on a drug test.

How Long Does Heroin Stay in Your System: Withdrawal

One reason many people will want to know how long heroin stays in the system is for the sake of overcoming their withdrawal symptoms. Especially for those who are familiar with suffering through these painful periods of abstinence, the question of how long does heroin stay in your system is about avoiding extended discomfort.

Withdrawal symptoms of heroin include:

  • Sweating
  • Insomnia
  • Malaise
  • Extreme anxiety
  • Depression
  • Itchiness
  • Excessive yawning and sneezing
  • Runny nose
  • Cold sweats
  • Chills
  • Severe muscle and bone aches
  • Nausea
  • Vomiting
  • Diarrhea
  • Fever
  • Cramp-like pains
  • Involuntary spasms in the legs, arms, and neck

Heroin withdrawals will not be the same for everyone. The same things that impact how long it stays in the system will also impact how severe the withdrawals are. Other substances that are used along with heroin will also have an impact on how serious the withdrawals can be and how long they may persist.
It has been estimated that heroin withdrawal symptom can start within 6-12 hours from the last dose and may be present up to 5-10 days.

How Long Does Heroin Stay in Your System: Overdose Danger

One big reason things like the half-life matter is because of how it increases the risks of overdose.

If we say that after ingesting heroin approximately 50% of the drug has been cleared from the body in somewhere between 8-30 minutes, what tends to happen during this time is that many people assume by time their “high” ends, most of the heroin is already fully cleared from their system. However, when the “high” ends, up to 50% of the heroin will still be in your system, and so will its metabolites! So while some people think the high wears off that quick so they may think it’s safe to do more, there is still a fair amount of that drug present in the body.

Although heroin is quickly metabolized and eliminated from the body, its metabolites remain present for a longer duration. When heroin is used it is de-acetylated into 6-monoacetylmorphine (6-MAM). This chemical then metabolizes into morphine. Morphine’s half-life is estimated to be between 1.5 and 7 hours. As a result, the morphine in the body created by using heroin could stay in your system for 1.60 days before it is entirely eliminated.

So when we ask how long does heroin stay in your system, it isn’t a one-size-fits-all thing. What we can say is that one thing the probably contributes a lot to the skyrocketing rates of overdoses and deaths is that people don’t understand the heroin half-life or how long it stays in the system.

The longer the drug is in the system, the harder it will be to detox from it. That is why medical detox is so crucial to effectively and safely getting off of heroin. It also shows why treatment can be critical to lasting recovery. If you or someone you love is struggling, please call toll-free now.

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